Osteoporosis

OsteoporosisOur bone is composed of protein, collagen, and calcium, to give bone its strength. Osteoporosis is a condition caused by a decrease in the density of bone, decreasing its strength and resulting in fragile bones. It leads to abnormally porous bone that is compressible, like a sponge. This disorder of the skeleton weakens the bone and results in frequent fractures in the bones. The leading cause of osteoporosis is a lack of certain hormones, particularly estrogen in women and androgen in men.

Osteoporosis can happen without any symptoms for decades since osteoporosis doesn’t cause symptoms until bone fractures. The common areas of bone fractures occurs in spine, hips, ribs, and wrists- although osteoporosis-related fractures can occur in almost any skeletal bone.

According to National Osteoporosis foundation, “About 10 million Americans already have the disease. About 34 million are at risk. Being at risk for osteoporosis means you are more likely to get this disease. Estimates suggest that about half of all women older than 50 will break a bone because of osteoporosis. Up to one in four men will too.” “In 2005, osteoporosis was responsible for an estimated two million fractures and $19 billion in costs. By 2025, experts predict that osteoporosis will be responsible for approximately three million fractures and $25.3 billion in costs each year.”  “Getting enough calcium, vitamin D and regular exercise are important for your bones. Eating fruits and vegetables is also good for bone health.”

Aftermath of Osteoporosis fracture lead to:

Risk factors and causes of Osteoporosis:

Diets rich in Calcium and Vitamin D:

Foods that provide vitamin D include:

Vitamin D Supplementation Inhibits Age-Related Bone Loss In Older Women

New research shows that vitamin D supplementation can reverse normal age-associated bone loss in postmenopausal women, which can lead to a reduced risk of osteoporosis and other bone disorders.

Until recently, it was unknown whether improving vitamin D status (without changing calcium intake) could have a positive effect on bone turnover.  New Zealand Researchers at Massey University recently measured the effect of vitamin D supplementation on markers associated with bone turnover in women known to be vitamin D deficient (<20 ng/mL).

Participants were South Asian women at least 20 years of age.  The women were categorized by age and menopausal status, and then randomized to receive either 4,000 IU of vitamin D or a placebo every day for 6 months.
In the women who received vitamin D supplements, average vitamin D blood levels increased from 8.4 ng/mL to 30 ng/mL.  Additionally, measured bone markers either stayed the same or decreased in postmenopausal women who received vitamin D supplements, indicating a potential reduction in bone turnover.  In postmenopausal women who received placebo, markers associated with bone turnover increased.  In younger, premenopausal women, no significant bone turnover change was reported for either placebo or supplementation group.

This research confirms that correcting vitamin D deficiencies in older women can suppress age-related increases in bone turnover, which also helps reduce bone resorption (the process by which bone breaks down and releases its minerals, resulting in a transfer of calcium from bone into the blood).

Source : von Hurst PR et al2010. J Steroid Biochem Mol Biol. EPub ahead of print, retrieved online 6 April 2010.

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One Response to “Osteoporosis”

Comment from Dann
Time January 10, 2015 at 1:24 pm

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